CrownLux®
- to protect healthy cells of the body from damage by oxidizing toxins, including nitrates and nitrites
- to reduce the intensity of inflammatory processes on the walls of blood vessels to prevent the formation and growth of blood clots
- to perform a complex age correction of the body and increase its vitality
- to cleanse the cell and intercellular space from lipofuscin
- to obtain a full projected anti-aging effect
- to significantly reduce the need for surgical treatment of pathological obesity in type 2 diabetes, it affects carbohydrate, protein and lipid metabolism
- regulates the processes in integrated physiological systems of the human body
- increases metabolic and regulatory processes connected with DNA molecular stability on various activity levels of the body — in cells, tissues, organs and systems
- has a positive effect on the aggregation of red blood cells and blood viscosity, reduces inflammatory processes on the blood vessels walls, reducing the risk of blood clots and has a dose-dependent light vasodilator effect
- inhibits the aging process of the human body
- increases vitality and libido
Pilot studies preliminary results of the effect of dietary supplements on human health showed a complex rejuvenating effect of the body, slowing down the tempo of functional aging, decreasing of the functional (biological) age, improvement of cognitive activity, attention, mental and physical performance and decreasing of cholesterol levels in the blood.
Any person, which takes CrownLux can have a free check up on the confidential basis for the resulting anti-aging effect, he will see the correction of his/her biological age and improvement of the performance and functional state of the body and thus will be able to see himself/herself effectiveness of CrownLux. The check up is made (as specified in the contract) according to the approved program of state institution D. F. Chebotarev Institute of Gerontology of the National Academy of Medical Sciences of Ukraine by the order of company Crown Farma.
Observations on the effects of dietary supplement on the human body have been carried out since 2009 at the Institute of Gerontology and in the anti-aging clinic Medicom (2009-2011) as well. The observations are characterized by positive changes in health indicators (general well-being, skin, digestive, cardiovascular, genitourinary and endocrine systems) and a number of other positive results in both men and women.
CrownLux is an oral form of gerontological injectable drug with a delicate qualitative anti-aging effect on the human body. CrownLux is available on the market in three versions:
- CrownLux 15
- CrownLux 30
- CrownLux 60
And it permits to determine the product optimal dosage for every person in order to achieve the most effective result.
CrownLux is an investment in your health. You will feel younger, more active and energetic. After the 1st course of treatment with the medicine your biological age will decrease significantly and the rate of aging will slow down.
Contradictions: cancer.
You can read in detail the characteristics of the dietary supplement and its capabilities in the instructions for use.
Technical Specification (Ukraine): ТУ У 10.8-40893378-001:2016
Barcode: EAN GTIN-13, 4820208230018
Security Certificate dated July 31, 2017 No.3/8-А-3811-17-64752Е
Conclusion of State sanitary-epidemiological expertise dated December 5, 2016
Registration No. 602=123-20-2/2525
Trademark Registration Certificate: 255416 (UA)
Trademark Registration Certificate: 255417 (EN)
SOME MORE INFORMATION ABOUT LONGEVITY AND ANTI-AGING PROGRAM CROWNLUX(CROWNLUX) ANTI-AGING EFFECT
Active creative and professional longevity is a very important topic for many. Active life position, high professional experience, profound knowledge accumulated during a long period require active self-realization at the stage of adulthood. Extending a healthy life for several decades is possible now. The view on ageing has changed significantly in recent decades. Maintaining high physical and social activity, support of age-friendly society and environment, constant training and retraining both in the professional sphere and in everyday life, high daily requirements for cognitive abilities of a person regardless of age has become the social norm of individual success of each unique personality.
Why do people age?
Starting from birth and throughout the whole life human cells constantly accumulate such structures as old defective mitochondria, peroxysomes, lysosomes and “broken defective proteins”, epigenetic mutations, free radicals triggering the processes of apoptosis (programmed cell death) and premature aging, which are commonly called cellular garbage (CG) lipofucsin.
Lipofuscin pellets are wastes from the body, its life — defective proteins, disposed and dead cells that are unable to re-engage key metabolic reactions. CG is one of the types of damage (breakdowns) at the cellular level, which prevents the normal functioning and harmonious interaction of human cells in metabolism and is the main cause of aging and numerous diseases (including cardiovascular and oncological diseases, diabetes, neurodegenerative changes and diseases of the musculoskeletal system, lungs and etc.)
Non-aging is moral and good. There is a very simple ethical logic behind this statement — if life and active longevity are the highest values and reducing the burden of suffering from disease is another value, then prolonging life by compensating age-dependent processes and diseases, improving the quality of life is as high a priority as caring for children and the elderly. Ultimately, the goal of longevity supporters is to improve quality of life and prolong life!
Lipofuscin is an autofluorescent pigment (from yellow to brown in colour) of glycolyprotein nature contained in all organs and tissues; it consists of oxidized and transversely stitched proteins and lipids, which makes it difficult to degrade and excrete it from cells. It contains phospholipids, cholesterol, triglycerides, fatty acid oxidation products and various enzymes known as amino acids. Lipids make 20-50%, proteins make 30-60% and 9-20% are iron-containing residues of black colour, which are not hydrolysed. The percentage of lipofuscin depends on the organ in which it is formed. The accumulation of lipofuscin has two stages — the so-called early pigmentation and late pigmentation. Lipofuscin in early stages is pale yellow in colour and lipofuscin in late stages already has pellets and its colour turns brown. The pigment is accumulated in lysosomes, peroxisomes and/or inside mitochondria. Physiological and pathological processes in the body influence the amount of lipofuscin.
The presence of lysosome enzymes (alkaline phosphate) in lipofuscin suggests that oxidative stress may cause the appearance of lipofuscin. The nature of the accumulation of lipofuscin in cells is associated with the destruction of cellular organelles, which have not been disposed by lysosomes.
Lipofuscin takes part in programmed cell death. In the early years of life, the impact of cellular debris is compensated by the coordinated work of free-radical oxidation enzymes, activation of the apoptosis system and hormonal regulation by the type of feedback, so, normally it almost does not appear. However, over the years, aggressive metabolic products gain the critical mass as the result of metabolism, consumption of «unhealthy» food and decreasing of activity. Therefore, a breakdown occurs and the process of accelerated aging is started. As a result of decompensating of the harmony processes of aging and anti-aging, age-dependent diseases start to develop.
The main sources of cellular garbage (CG) are the following:
- the metabolism, which even under favourable conditions “fails” from a young age, deforming and disabling the cells of the human body
- certain types of ingredients in modern food products that enter the body during the digestion processes are converted into harmful substances that destroy cells inside and out
- when cellular fragmented structures are not excreted from the body, they accumulate, lead to various dysfunctions of organs, system and diseases
Results of degenerative processes of premature aging are as follows:
Dystrophic formations that envelop the cell from the outside. They are formed from “bad” cholesterol. Its main source are the degenerative processes of protein, lipid and carbohydrate metabolism although the basic nutrients come from everyday food.
- The cellular garbage (CG) accumulated inside cells. Most of cells divide 50 times in their entire life. Filling with garbage, separate cells prematurely “burn down” without fulfilling their program
- The cellular garbage (CG) from self-destructing cells — some cells with excessive debris commit suicide themselves
- Degenerative fragments from cross-stitches. Once in the body, carbohydrates “stitch” molecules of proteins. Cells stop normal functioning. This negatively affects the quality of blood vessels, the tissues lose elasticity and the body becomes flabby
To destroy this ballast in the cells, special incinerators work, they are called lysosomes. Lysosomes act as cell cleaners and take part in the recycling of organic cell material and intracellular «digestion» of macromolecules. They are necessary for the degradation of intracellular components (organelles).
The degradation of the cellular components and macromolecules for disposal occurs in the lysosomom under the influence of special fissile enzymes, one of which is alkaline phosphatasis. Cleaning of cell fragments and damaged cells is carried out with the help of an army of macrophages, which are the immune guardians of the body. Macrophagues cope with their task well, absorbing and neutralizing dangerous substances in a healthy young body. With age or due to serious diseases, people have age-related and pathological accumulations of intracellular waste.
Lipofuscin levels as a biomarker of aging.
Lipofuscin doesn’t cause a disease. Its presence only indicates a change in the functioning of cells, it is an indicator of lysosomes and mitochondria disruption, which leads to the deterioration of cell metabolism, which in turn indicates the approaching of apoptosis and is a symptom of pathology of cells, tissues and organs in the human body.
The mitochondrial—lysosomal axis theory of aging most clearly defines the connection of lipofuscin with aging, according to which the age related accumulation of lipofuscin cluttering lysosomes is closely associated with the progressive violation of autophagy, oxidative stress and dysfunction of mitochondria.
Lipofuscin is an important sign of aging in the whole. It has been established that life expectancy decreases with the increase in accumulation of lipofuscin. Lipofuscin causes a gradual age-related accumulation of damaged mitochondria, other types of organelles and, as a result, cell dysfunction of post-mytotic cells, organ dysfunction and their aging. Lipofuscin is accumulated in the cells of the brain, heart, retina, skeletal muscles, skin and other organs. Therefore, lipofuscin is used as a biomarker of aging.
What influences accelerated accumulation of lipofuscin?
- Regular over-consumption of iron-containing foods and saturated fatty acids
- Chronic alcohol consumption
- Overactive exercise also often stimulates accelerated accumulation of lipofuscin in the liver, kidneys and skin
- In case of lipofuscinoses
- Fragments of this pigment are involved in the formation of the protein that plays a direct role in the development of dementia, Alzheimer’s and Parkinson’s diseases
- Lipofuscin exacerbates cardiovascular disease
- Lipofuscin can disrupt the function of retinal cells and cause diseases such as age-related macular degeneration
- Lipofuscin causes trophiс dysfunctions, cardiac and liver diseases
- Lipofuscin causes degeneration processes that impair musculoskeletal function
- Lipofuscin significantly affects skin aging process
CONCLUSION
As world scientific community states, in spite of numerous studies on the prevention and reduction of lipofuscin, modern science does not have effective tools to remove lipofuscin.
We are optimistic about the future and affirm that such drugs and products created by our team of scientists do exist and the evidence of it are the unsurpassed results of the research conducted in leading innovation laboratories and clinics
