Tiosan

Dietary supplement TIOSAN® — new possibilities for patients

Pharmaceutical company Crown Farm registered a new product in 2016, it is dietary supplement TIOSAN, an oral dietary supplement intended for use as a means to optimize the treatment of malignant neoplasms (Conclusion of the state sanitary and epidemiological expertise No.602-123-29-2/2525 dated 05.12.2016., ТУ У 10.8-40893378-001:2016; protocol of expertise No.3/8-А-3811-17-64752Е dated 31.07.2017).

Clinical research on the use of dietary supplements TIOSAN in patients diagnosed with glioblastoma and anaplastic glioma (2 clinical trial protocols) has been made at A.P. Romodanov Institute of Neurosurgery of the Academy of Medical Sciences of Ukraine starting from December 2017 and to date. 

SubjectsDiagnoses

Medical Institutions/

Head of Research

Form of administration
Tolerance and efficacy

·         glioblastoma

·         anaplastic glioma (anaplastic astrocytoma, anaplastic  oligodendroglioma, anaplastic oligostrocytoma)

Chief neuro-oncologist of NAMS of Ukraine, head of the Pediatric
neuro-oncology and neurosurgery department at A.P. Romodanov
institute of NAMS of Ukraine, corresponding member of NAMS of
Ukraine, professor, Doctor of Medical Science, Vladimir
Rozumenko

Solution for per oral administration

Preliminary results indicate the positive effect of this product on the course of treatment of intracerebral III and IV cancer stages (degrees of malignancy).

TIOSAN improves the quality of life of patients and it does not cause side effects and is not toxic.

The reaction to the product is often manifested by a slight increase in the patient’s body temperature in the first 3 to 5 days after the administration, which indicates a response of the immune system of the body and does not require special treatment.

No addiction to the product drug has been defined to date.

On April 7, 2020, the Institute approved the 1st stage of the report on the progress of 2 protocols on the theme Morphological Evaluation of the Radiation Therapy and Dietary Supplement TIOSAN Combined Use Effectiveness in Malignant Brain Gliomas.

The results of histological studies show the reaction (sensitivity) of tumour cells to the dietary supplement under study, TIOSAN; signs of therapeutic pathomorphosis in the form of an increase in the processes of coagulation necrosis, accumulation of picnomorphic and giant-nuclear cells has been defined. At the same time, the presence of newly formed glomerular vessels is not observed, which is a favorable predictive factor.

TIOSAN is safe for to use.

TIOSAN can be used in the treatment of various cancer processes. Data on its effectiveness has been accumulating.